In this issue

はじめに

Gut誌に掲載された優れた論文の中から抄訳論文を選択するにあたり、ヒトを対象とし、わが国にも重要な意義を持つ臨床研究論文であることを基準とした。消化器病学の最新動向を把握する一助となれば幸いである。

Gut日本語版編集委員長　菅野健太郎（自治医科大学名誉教授）

CONTENT

Vol.1 No.5

Gut microbiota

IBS患者の便中細菌プロファイルの多変量モデリングにより低FODMAP食に対する反応を予測する

Multivariate modelling of faecal bacterial profiles of patients with IBS predicts responsiveness to a diet low in FODMAPs

Sean M P Bennet,^1,2 Lena Böhn,^1,3 Stine Störsrud,^1,3 Therese Liljebo,⁴ Lena Collin,⁵ Perjohan Lindfors,^1,5,6 Hans Törnblom,^1,3 Lena Öhman,^1,2,7 Magnus Simrén^1,3

Stomach

胃癌発生における粘膜細菌叢の構成異常

Mucosal microbiome dysbiosis in gastric carcinogenesis

Olabisi Oluwabukola Coker,¹ Zhenwei Dai,¹ Yongzhan Nie,² Guijun Zhao,³ Lei Cao,¹ Geicho Nakatsu,¹ William KK Wu,¹ Sunny Hei Wong,¹ Zigui Chen,⁴ Joseph J Y Sung,¹ Jun Yu¹

Endscopy

潰瘍性大腸炎の色素内視鏡検査対狭帯域光観察：前向き無作為化対照試験

Chromoendoscopy versus narrow band imaging in UC: a prospective randomised controlled trial

Raf Bisschops,¹ Talat Bessissow,^1,2 Joseph A Joseph,² Filip Baert,³ Marc Ferrante,¹ Vera Ballet,¹ Hilde Willekens,¹ Ingrid Demedts,¹ Karel Geboes,⁴ Gert De Hertogh,⁴ Séverine Vermeire,¹ Paul Rutgeerts,¹ Gert Van Assche¹

Hepatology

肝硬変における真菌の構成異常

Fungal dysbiosis in cirrhosis

Jasmohan S Bajaj,¹Eric J Liu,² Raffi Kheradman,² Andrew Fagan,¹ Douglas M Heuman,¹ Melanie White,¹Edith A Gavis,¹ Phillip Hylemon,¹Masoumeh Sikaroodi,¹Patrick M Gillevet²

Colon

前癌状態の結腸直腸腺腫の体細胞変異の全体像

The somatic mutation landscape of premalignant colorectal adenoma

Shu-Hong Lin,^1,2Gottumukkala S Raju,³Chad Huff,¹ Yuanqing Ye,¹ Jian Gu,¹ Jiun-Sheng Chen,^1,2 Michelle A T Hildebrandt,¹ Han Liang,⁴ David G Menter,⁵ Jeffery Morris,⁶ Ernest Hawk,⁷ John R Stroehlein,³ Andrew Futreal,⁸ Scott Kopetz,⁵ Lopa Mishra,³ Xifeng Wu¹

Gut microbiota

75歳以下のpath_MMRキャリアにおける遺伝子別および性別の癌リスクと生存：Prospective Lynch Syndrome Databaseに基づく報告

Cancer risk and survival in path_MMR carriers by gene and gender up to 75 years of age: a report from the Prospective Lynch Syndrome Database

Pal Moller,^1,2,3 Toni T Seppala,⁴ Inge Bernstein,^5,6 Elke Holinski-Feder,^7,8 Paulo Sala,⁹D Gareth Evans,^10,11 Annika Lindblom,¹² Finlay Macrae,^13,14 Ignacio Blanco,¹⁵ Rolf H Sijmons,¹⁶ Jacqueline Jeffries,¹⁷Hans F A Vasen,¹⁸ John Burn,¹⁹ Sigve Nakken,² Eivind Hovig,^2,20,21 Einar Andreas Rodland,² Kukatharmini Tharmaratnam,²²Wouter H de Vos tot Nederveen Cappe^l,23 James Hill,²⁴ Juul T Wijnen,²⁵ Mark A Jenkins,²⁶ Kate Green,^10,11 Fiona Lalloo,^10,11 Lone Sunde,^6,27,28Miriam Mints,²⁹ Lucio Bertario,⁹Marta Pineda,¹⁵ Matilde Navarro,¹⁵Monika Morak,^7,8 Laura Renkonen-Sinisalo,^4,30 Mev Dominguez Valentin,^1,2 Ian M Frayling, John-Paul Plazzer,¹³ Kirsi Pylvanainen,³¹ Maurizio Genuardi,³² Jukka-Pekka Mecklin,³³ Gabriela Moeslein, Julian R Sampson,¹⁷ Gabriel Capella,^15,34 in collaboration with The Mallorca Group